These are our 10 most cited Emergency and Critical Care reviews for 2021.

Congratulations to the author teams who produced these reviews, and to the editorial teams who supported their production! Many of these reviews have been cited in evidence-based clinical guidelines. 

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis

Perioperative restrictive versus goal-directed fluid therapy for adults undergoing major non-cardiac surgery

Peripheral nerve blocks for hip fractures in adults

Epidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass

Perioperative beta-blockers for preventing surgery-related mortality and morbidity in adults undergoing non-cardiac surgery

Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non-cardiac surgery

Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting

Adductor canal blocks for postoperative pain treatment in adults undergoing knee surgery

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta-analysis

Perioperative beta-blockers for preventing surgery-related mortality and morbidity in adults undergoing cardiac surgery